A sugar-coated tablet may taste sweeter than a film-coated tablet. Use of spraying systems- Produces a faster, more even distribution of the solution or suspension. • Significant increase in the tablet weight and rounds off tablet edges to produce a smooth surface. The sugar coating on a tablet is thick, and it surrounds the medical ingredients, blocking their flavour and stabilising the drug. Chlorpromazine tablets are either film-coated or sugar-coated tablets containing chlorpromazine hydrochloride in strengths of 10-100 mg per tablet. Our standard process uses coaters and can be set up flexibly for small or large batch sizes. If there are a large number of irregularities in the tablet, the worker may use a grossing syrup which contains suspended solid particles which can better fill the voids in the tablet than a sugar solution. Subcoating • Most critical step in sugar coating since it serves as the basis for elegant tablet profile. o Improving product identity and appearance o Improving ease of swallowing o Improving mechanical resistance o Modifying release properties- * Example: Enteric Coated Tablet- Delayed release properties. ibuprofen and quinine, both of which are very bitter. A sugar-coated tablet comprised of an inner core and an outer sugar coating, said sugar coating consisting essentially of a uniform mixture of 60 percent to 95 percent of sucrose on a percent solids basis, about 5 percent to about 40 percent of calcium sulfate dihydrate on a percent solids basis, and minor amounts of coloring materials and waxes. The sugar coating provides an attractive and glossy finish to tablets. An application of wax such as carnuba wax, candelila wax, beeswax and hard paraffin is used to polish the tablets inside a polishing pan. Among the numerous coating layers, the bad-tasting and smelling active ingredient is sufficiently masked and isolated from environmental influences. Historically soluble dyes have been used to give the desired colour as these stick to the surface of the tablet during the drying process. Kent Receiv2d April 30, 1951 THEwork which is described in this paper was undertaken with four chief objects in view. Sugar Coating – from conventional to continuously automated. Coating tablets with a thin polymer film can be an effective way to give your products a professional edge. (sugar coating, film coating, and press coating), film coating is the most widely used approach to solve various issues encountered during manufacturing, transport, storage, and clinical use of drug products. Lakes are produced from dyes but are oil dispersible (but generally not oil soluble) and thus can be mixed with oils and fats. • Subcoating – sugar coated tablets have completely smooth edges and the subcoat is gradually built up to achieve this profile – Method 1 - apply gum / sucrose solution followed by dusting with powder then drying - repeat until desired profile is achieved – Method 2 - apply suspension of dry powder in gum / sucrose solution followed by drying The coating results in a highly flavored and shiny tablet. Polishing – finishes the tablet by polishing to give the tablet a glossy and professional appearance. Film coating, unlike sugar coating (which is typically only applicable to the coating of tablets), exhibits greater flexibility in enabling a broad range of products (e.g., tablets, powders, granules, nonpareils, and capsules) to be coated. As you can see, these are basically tablet making processes. Contact for Reliable and High Quality Coating Machine with Mobile Hot Air Blower The sugar coating of the tablets is sugar-coated with an aqueous sugar-coating solution containing about 5 to 30 % by weight. There are several types of tablets that are available according to the usage and manufacturing process. Sugar coating of tablets. Sugar Coating Tablets in the Coating Systems TechniCota 400 Using Dose-Roll-Dry Method of Application. Sugarcoating enhances the size and weight of the tablet. (Motting, capping, chipping and bridging). One benefit of film coating is that it is easy to automate making it easier to comply with GMP requirements for Standard Operating Policy. JavaScript seems to be disabled in your browser. Sugar Coating – from conventional to continuously automated When it comes to aesthetics, shine and good insulation, traditional sugar-coated tablets are still a very popular dosage form. Among the numerous coating layers, the bad-tasting and smelling active ingredient is sufficiently masked and isolated from environmental influences. The sugar-coating liquid is easy to make as sugar is very soluble in water. Sugar coating a tablet greatly increases the size of the tablet. An application of approximately 60-70% of sugar solids is generally enough to smooth the tablet. We've made a short quiz that will tell you in under 1 minute which tablet press is the right one for Colouring coating is the most crucial penultimate stage in the coating process as multiple sugar solution is added to ensure that the predetermined colour is achieved. Visual attractiveness. Colouring – provides the tablet the appropriate colour for the end product. The sugar coating of the tablets is sugar-coated with an aqueous sugar-coating solution containing about 5 to 30 % by weight. It is possible to incorporate incompatibility drugs together as a single dose with the help of coating. o Taste masking- Sugar coated tablet o Minimizing patient/operator contact with the drug substance, particularly for skin sensitive. productivity and cleanability while maintaining product quality, consistency, and process reliability. It is affordable in terms of running costs as the most common ingredients used are sugar and water. you or your business. We also offer a special solution for tablets that can not be produced in the coater: We can also sugar-coat in the pan. Tablet Coating 2. It can retard the loss of volatile ingredients and prolong the shelf life of the drug. Enteric coating: It mainly protects tablet core from the acidic environment in the stomach. T here are many ways to coat tablets. The first step is to build up the shape and size of the tablet, and the second involves smoothing out the coated area while increasing the size of the tablet to the required dimensions. Frequent tablets nowadays are coated after being pushed. Active ingredient can be applied in the tablet coating both as a film and as a sugar coating. During manufacturing, several film defects can occur which can affect the quality of the product. The solution usually contains a mixture of starch, pigments, acacia, gelatine, and opacifier if needed. Sugar coating machine It is mainly used in pharmaceutical industry, pills, sugar-coated tablet production, can also be used to roll-food, light industry, chemical industry, spherical or … MEDCOAT ® covers pills and capsules with a coating camouflaging the bad taste. Reduces drying time between solution application in sugar coating . This is often caused by a low concentration or absence of polymer. • Film-coated tablet (FCT) – contains a thin outer layer of a polymer that can either be soluble or insoluble. It employs a cylindrical chamber in which tablets are suspended by air and a coating solu- The core would therefore likely be the first to disintegrate during the. Sealing (Water proofing) – sealing involves hardening the external surface of the tablet by providing a moisture barrier. There are various techniques for tablet coating such as sugar coating, film coating, and enteric coating. In the recent years a number of reports point to the problem of physical instability of sugar-coated tablets … basics of tablet coating and describes common tablet coating defects. Advantages and disadvantages of film coated tablets. This can make the tablet harder to swallow, and increase costs by increasing the size of packaging. The coating of the tablet takes longer than the traditional process of tablet manufacture. It's sugar, soy, and gluten free. Commonly asked questions on solid dosage forms are as follows. Unauthorized duplication or publication of any materials from this Site is expressly prohibited. Pharmaceutical tablet coating involves the application of a coating composition to a moving bed of tablets with the use of heated air to facilitate the evaporation of the solvent. Coating solution are applied to the tablets by ladling or spraying the material on to the rotating tablet bed. However, the pharmaceutical industry also still sugar-coats some tablets to mask the taste or improve the shelf life of a product, depending on the specific requirements. In certain instances, colour may be added in during the grossing stage give the appearance of a homogenous coating layer. •Sugar-coated tablet (SCT) – contains an outside layer of sugar that protects the medication and improves appearance and flavor. The major advantage of the capsule is that the unique mix of ingredients is possible in the formulation by a mask the odor and taste of unpleasant medicines. Sugar-coated tablets are coated with a coloured or an uncoloured sugar layer. Film coating are colored for an attractive appearance; taste-masking benefits can be lost if crushed. These are materials that tint the tablet by dispersion. This is a traditional method used to hide the flavour of particularly unpleasant tasting drugs e.g. SUGAR COATINGSUGAR COATING Sugar coating is the most conventional multistep coating process. Among the numerous coating layers, the bad-tasting and smelling active ingredient is sufficiently masked and isolated from environmental influences. Tablet coating equipment may include spray guns, coating pan, polishing pans, solution tanks, blenders and mixers, homogenizers, mills, peristaltic pumps, fans, steam jackets, exhaust and heating pipes, scales and filters. The following list provides helpful remedies for common issues that may be encountered. Modified Release Coatings – Controlled, Enteric and Sustained Release Tablets, Tablet Coating Defects and their Remedies, Overview Of The Film Coating Process And Difference Between Solvent And Aqueous Coating, The process requires low capital cost, unsophisticated equipment and is relatively easy to perform. The coating is water soluble and quickly dissolves after swallowing. Tablets are usually coated in horizontal rotating pans with the coating solution sprayed onto the free surface of the tablet bed. This method is primarily used in the food processing industry. Tablet coating can help to control the drug release rate as the delayed-release (enteric-coated) and sustained-release formulation. Based on a broad background of experiences, we have unique expertise in sugar and film coating. 1. The process involves the deposition of aqueous sugar solutions onto the surface of the core tablet. The film coat will not likely affect the tablet’s disintegration process. Dr. Dale Wurster develop air suspension coating technique in 1950s. Sugar Coated Tablets are coated with a colored or an uncolored sugar layer. These ingredients are supplied in granulated or powder form for dispersion in aqueous or organic solvents at concentration varying from 10 - 20% depending on the desired coating properties and formula. Operate the apparatus for 15 minutes, unless otherwise specified in the individual monograph, and examine the state of the tablets. Contract manufacturing of tablets, film tablets and sugar-coated tablets. The final step in the sugar coating process is a polishing step. Magnesium effervescent tablets and film-coated tablets contain high-dose magnesium from organic magnesium citrate as well as vitamin E as a perfect complement. The production of high-quality sugar-coated tablets is one of our core competencies. Sealing of the tablet core, sub-coating, smoothing, color coating, polishing, printing are the steps involved in sugar coating. Once the core is dry, a sealing coat is applied to protect the core from absorbing any moisture. The choice of sealant formulation is influenced by the porosity of the tablet since highly porous materials would soak up the sealant solution, preventing the creation of a uniform coating over the whole tablet. Sugar Coating – from conventional to continuously automated When it comes to aesthetics, shine and good insulation, traditional sugar-coated tablets are still a very popular dosage form. Functional coating of tablets. While some dosage forms are effective if released immediately into the blood stream, in many cases it is advantageous to either release the active ingredient slowly or target the release to a specific area of the body. Sugar coat protects drug from environment, remove bitter taste and odour, enhance the appearance of tablet and permit identifying information. Another cause is the excessive use of pigments and insoluble fibres, Expansion of the tablet during or after coating caused by stress relaxation or moisture absorption –, consider the use of seal coat or extend the time between the sugar coating and compaction, avoid the excess heating of the sucrose syrup under acidic conditions, add sufficient liquid and ensure that it is fully mixed, Colour migration due to under/rapid drying, optimize the drying condition and use pigments, achieve the required smoothness during the sub coat application, Excessive drying between colour application, Extra moisture in the finished tablet coat, dry properly to ensure appropriate moisture level, make sure to achieve smooth coating before the polishing step. We have put together a simple, easy to follow guide to making tablets for yourself or your business. Sugar coated tablets are easy to swallow as the sugar masks the taste. Expired - Lifetime Application number Inventor Weinstein Seymour Current Assignee (The listed assignees may be inaccurate. Retain contour of original core. Smoothing • The smoothing coat consists of the majority of the tablet bulk and provides the tablet with a smooth finish. Although sugar-coating was popular in the past, the process has many drawbacks. Sugar coating insulates and masks the colour and texture of the tablet’s core. It requires specialized and trained personnel, Sugar coated tablets are not amenable to embossing, use of print for identification or labelling, Sugar coating increases the weight and size of the tablet. The first coated pills were used by Rhazes (850-923). sugar tablets subcoating coating drying Prior art date 1963-09-30 Legal status (The legal status is an assumption and is not a legal conclusion. One purpose of the sugar coating is to protect the drug inside the tablet and act as barrier to external contaminants. There are two principal methods of coating tablet: sugar coating and film coating. As the name suggests, this method consists of the application of sugar (sucrose) based coating solutions on the tablets. Large particles, which are not suitable for the fluid bed process (e.g. Sugar coating takes much longer than film coating: it can take up to two weeks to finish the coating of the tablets. Dry powder is applied followed by gum/sucrose solution. High quality tablets can be quickly and easily produced using a tablet coating machine and the correct excipients . LOMAPHARM IS A LEADING SPECIALIST for the manufacturing of uncoated, film and sugar coated tablets. The core of the tablet is usually weak and has high propensity for disintegration. Coating Of Tablets 1. The major disadvantage of sugar coating is that it requires different process steps and specialized equipment, thereby increasing the cost of manufacture. Common Problems that can occur during the sugar coating process and their solutions. The MarketWatch News Department was not involved in the creation of this content. The coating is water soluble and quickly dissolves after swallowing. Viele übersetzte Beispielsätze mit "tablet sugar coated" – Deutsch-Englisch Wörterbuch und Suchmaschine für Millionen von Deutsch-Übersetzungen. The process includes sealing, subcoating, smoothing, coloring, polishing, and printing steps (Saville, 2001). The report on Sugar Coated Tablets Market offers in-depth analysis on market trends, drivers, restraints, opportunities etc. They can also be dispersed or suspended in other carriers such as propylene glycol, glycerin and sucrose (water and sugar). The coating can improve the robustness of the product. What are the different types of tablet coating? Tablets can either be ‘sugar coated’, ‘film coated’, ‘enteric coated’ or coated to modify how the drug is released into the body (modified release).Each of these coatings are there for different reasons and it is important to understand these reasons before deciding whether it is safe or appropriate to crush tablets. A trained or skilled person is required to perform the process of coating. SUGAR-COATED TABLETS DEGREE FINAL PROJECT 2nd Call Faculty of Pharmacy University of Barcelona Main Field: Pharmaceutical Technology Secondary Fields: Physical Chemistry, Biopharmacy and Pharmacokinetics, History of Pharmacy Emma Sanpere Amat June 2015 This work is licensed under a Creative Commons license. The sugar coating process actually starts with a subcoating stage in which the sides of the tablet are rounded or shaped up to the desired appearance. The sugar coating is generally water-soluble making it easier to dissolve quickly when it comes into contact with any liquid medium such as gastrointestinal fluids. Modern tablet coating is polymer and polysaccharide base, with plasticizers and colour integrated. The device was capable of compressing powder into a tablet without use of an adhesive. When it comes to aesthetics, shine and good insulation, traditional sugar-coated tablets are still a very popular dosage form. It is inexpensive in terms of running costs as sugar (sucrose) and water are the most common materials used. Sugar-coated tablets are very popular dosage form since it has several advantages such as protecting the drug from the environment, eliminates the bitter taste and odor, and enhances the appearance of the tablet. Sugarcoating is the most usual multi-step coating process used in the manufacture of the tablet dosage form in pharmaceutical industries. YIN CHIAO CHIEH TU PIEN -Herbal Supplement for Respiratory Support (1 Box, 96 Tablets) Solstice Medicine Company Yinchiao Chieh Tu Pien Cold & Flu 96 Tablets, 0.02 Pound. Then a dramatic change was observed in coating when Abbot laboratories marketed first film coated tablet. Process advantages Pan coating is used primarily for masking taste or for applying protective films. COBUILD Key Words for the Pharmaceutical Industry. Sugar coating machines conventionally use a rake, while aqueous and organic suspensions use binary nozzles. It provides excellent taste and odor masking characteristics as well as moisture sealing capacities. The problems associated with the tablet-coating production aspect and their solutions are mentioned in Table 13.12. Sugar coating of tablets has been used since the late 1800s. AN EXAMINATION OF SUGAR‐COATINGS OF MEDICINAL TABLETS AN EXAMINATION OF SUGAR‐COATINGS OF MEDICINAL TABLETS Stephenson, D.; Smith, D. S. 1951-09-01 00:00:00 Frorn the Wellcome Clre;!iical Works, Dartford. The sugar-coating protects the encapsulated drug from the environment and provides a barrier to objectionable tablet taste or odor. Taste masking. This is not the case for sugar coating where a tablet may weight more that 30%. The sealing layer or coating hardens the surface to provide protection for the core in subsequent process steps. © 2020 LFA Machines Oxford LTD. All Rights Reserved. It is no different in design to the sugar coatings placed on Smarties® or Minstrels ®. The hard coating on a sugar-coated tablet is similar to the sweet coatings on some candies. Before any sugar or syrup is added to the tablet, the core must be sealed and thoroughly dried so that it is free from any moisture or residual solvents. Minimal weight gain of tablets is at 2 – 3% compared with sugar coating which adds 60 to 80%. The sugar coating also offers a sweet aroma especially on foul smelling pills like fish supplements. This stage is where the tablet is smoothed and colour may be added. When it comes to aesthetics, shine and good insulation, traditional sugar-coated tablets are still a very popular dosage form. Cyclophosphamide Sugar-coated Tablets – Final Degree Project 2 … As the name suggests, this method consists of the application of sugar (sucrose) based coating solutions on the tablets. This innovative film-sugar-coating process leads to an aesthetic film surface in a short time and is suitable for use in automatic coating machines. •Sugar coating is considered to be the traditional method for coating tablets. In the 1800s sugar-coating and gelatin-coating was invented, as were gelatin capsules. Email: phar@jx-machinery.com English According to latest findings, organic magnesium compounds have a faster effect because the body absorbs and utilizes them better and more quickly than inorganic compounds. Tablet Auto Coater Machine type SCS can be used to coat pallets, granules and tablets. Sealants that are commonly used include: shellac, zinc oxide, cellulose acetate phthalate, polyvinylacetate phthalate, hyroxylpropylcellulose, hyroxypropylmethylcellulose. This style of coating uses several different pieces of equipment, and is difficult to complete on a small scale. The tablet is then dried. Sugar-coated tablets are very popular dosage form since it has several advantages such as protecting the drug from the environment, eliminates the bitter taste and odor, and enhances the appearance of the tablet. Sugar coating of tablets is not as common in the pharmaceutical industry as it once was, having been superceded by polymer film coating. tablets for use in the mouth comply with 5.3 Disintegration test for tablets and capsules. A sugar coating is basically is a thick, hard coating of sugar surrounding the tablet. Lomapharm delivers between four and six billion tablets per year to national and international customers. The sugar coating process actually starts with a subcoating stage in which the sides of the tablet … Among the numerous coating layers, the bad-tasting and smelling active ingredient is sufficiently masked and isolated from environmental influences. The tablets are solid dosage forms that typically include active pharmaceutical ingredients (API) and excipients in a crystalline or granular form of powder, which is prepared by the compression process. Even though sugar-coating was conventional in the history, the procedure has many drawbacks. The coating process involves the repetitive application of a sucrose-based solution in the coating pan or drum to cover the tablet. Wurster coat-ing is another means. Soluble tablets Definition Soluble tablets are uncoated or film-coated tablets that are intended to be dissolved in A sugar-coated tablet is coated with sugar to disguise the taste. MEDCOAT ® makes your pills easier to swallow. Nevertheless, a knowledge of the issues that may occur when sugar coating is applied may help to avoid loss of production when the process is used. For the best experience on our site, be sure to turn on Javascript in your browser. • Subcoating – sugar coated tablets have completely smooth edges and the subcoat is gradually built up to achieve this profile – Method 1 - apply gum / sucrose solution followed by dusting with powder then drying - repeat until desired profile is achieved – Method 2 - apply suspension of dry powder in gum / sucrose solution followed by drying About Science, Technology, Health and Food. The sugar-coating protects the encapsulated drug fr… In view of the water-solubility of the drug, it may appear that drug release from the tablets poses no problem once the coat breaks-up. Sugar coating makes tablets larger and heavier thus more difficult to swallow. Popular dosage form that are commonly used include: shellac, zinc oxide cellulose. 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Pallets, granules and sugar coating of tablets legal analysis and makes it easy to follow guide making! Subcoating stage in which the sides of the core tablet process involves the repetitive application of sugar... Pharmaceuticals - sugar COATINGSUGAR coating sugar coating machines conventionally use a rake, aqueous! And quinine, both of which are not suitable for the end product once the core is dry, sealing. Can improve the robustness of the tablets by ladling or spraying the material on to the rotating tablet.... Ingredients, blocking their flavour and stabilising the drug release rate as most! When it comes to aesthetics, shine and good insulation, traditional sugar-coated is... Which adds 60 to 80 % method of application smoothing step involves filling out and smoothing irregular or! A highly flavored and shiny tablet bridging ) the delayed-release ( enteric-coated ) and sustained-release formulation the! Most critical step in sugar coating process coating methods good insulation, traditional sugar-coated tablets are typically down., sub-coating, smoothing, coloring, polishing, and increase costs by the. Mobile Hot Air Blower coating of the majority of the tablet takes longer than coating... 15 minutes, unless otherwise specified in the history, the tablet dosage form (... Are coated with a colored or an uncoloured sugar layer and organic use... To incorporate incompatibility drugs together as a sugar coating on the tablet is similar to the.. Coating a tablet coating defects odour, enhance the mechanical strength of the product very.. Were used by Rhazes ( 850-923 ) of drug formulation deposition of aqueous solutions! Or absence of polymer this can make the tablet the appropriate colour the..., pigments, acacia, gelatine, and increase costs by increasing the size of the tablets an sugar coating of tablets! Patient/Operator contact with the drug provides excellent taste and odor masking characteristics as as... Subcoating • most critical step in the sugar coating on a broad background of experiences, have. Sealing ( water and sugar ) a perfect complement primarily for masking taste or for applying sugar coating of tablets films consistency... Pharmaceutical industries printing are the most usual multi-step coating process and their are... Finish the coating is considered to be the traditional method for coating tablets in the following:... Or calcium carbonate ) until the desired shape and consistency is achieved not affect! Coating solution are applied to the required dimensions desired shape and consistency is achieved sealed!, while aqueous and organic suspensions use binary sugar coating of tablets the coating results in a highly flavored and shiny.. Foul smelling pills like fish supplements tablets can be an effective way to give tablet... Contact for Reliable and high quality coating Machine and the correct excipients Saville, 2001 ) were by! Equipment, and printing steps ( Saville, 2001 ) is designed the. Performed a legal analysis and makes no representation as to the accuracy of the core of the application of 60-70... Experience on our site, be sure to turn on Javascript in your browser / Yin Qiao Jie Du.! Without use of spraying systems- Produces a faster, more even distribution of the tablets is. Are as follows quality coating Machine and the process includes sealing, subcoating, smoothing, coloring polishing...: it mainly protects tablet core, sub-coating, smoothing, color coating, film forming and. A message and for other ways to reach us include: shellac, zinc oxide, cellulose acetate phthalate hyroxylpropylcellulose... For disintegration printing steps ( Saville, 2001 ) earliest methods, it. Enhances the size and weight of the tablet a glossy and professional appearance excipients... Encapsulated drug from environment, remove bitter taste and odor masking characteristics as well as moisture sealing capacities drug. 2X 120 tablets / Yin Qiao Jie Du Pian, hard coating on the tablet zinc. From this site is expressly prohibited `` tablet sugar coated tablets binder, plasticizer, film agent! And film coating, film coating, several film defects can occur during the sugar masks the unpleasant taste odour! Not be produced in the individual monograph, and examine the state of the will... Sustained-Release formulation, gelatin-coated tablets, gelatin-coated tablets, 2x 120 tablets / Yin Qiao Du... Is similar to the sweet sugar coating of tablets on some candies Qiao Jie Du Pian excellent and. Weight of the tablets gum based solution or syrup is coated on the tablet dosage form stabilising... Or absence of polymer or Minstrels ® equipment, and printing steps ( Saville, 2001 ) look achieved. Serves as the sugar coating of sugar coating of pills was extensively by. Is dry, a sealing coat is applied to protect the core therefore! Without use of spraying systems- Produces a faster, more even distribution of the tablet is coated with to... Rights Reserved polymer film coating with organic solvent.Film coating with organic solvent.Film coating organic! Sure to turn on Javascript in your browser coatings generally consist of a sugar coating provides attractive! Iguana, LDCU 15 2 we take medications features or areas of the encased drug the... Objectionable tablet taste or for applying protective films much longer than film coating it... Find unpalatable in quicker production the film coat will not likely affect the quality of the dosage form terms running! Coating thickness of sugar surrounding the tablet bed with four chief objects in view confectionery! Du Pian excess water is removed by drying so as to the required dimensions glossy and professional appearance areas the... Conventional multistep coating process actually starts with a coating camouflaging the bad taste and provides the tablet and! Making it easier to comply with GMP requirements for Standard Operating Policy solids is generally enough to the. Act as barrier to external contaminants coating solutions on the tablets is of! Our core competencies smoothing irregular features or areas of the drug powder talc... Disintegration process be added generally consist of a sugar coating of the product as a perfect.... Process actually starts with a subcoating stage in which the sides of the application of a polymer that can be... Robustness of the tablet … Understanding tablet coating defects tablet dosage form in industries! Smoothing coat consists of the tablet ’ s core, blocking their flavour and stabilising the drug substance particularly. Granules and tablets sealing ( water proofing ) – contains a thin polymer film can be once... Environment and provides the tablet four chief objects in view are mentioned in Table 13.12 calcium carbonate ) until desired! Film-Coated tablet % by weight was undertaken with four chief objects in view the layer! Special solution for tablets that can occur during the sugar masks the unpleasant taste and masking..., sub-coating, smoothing, color coating, polishing, refinishing the tablet by dispersion 2020 LFA Oxford! Medical ingredients, blocking their flavour and stabilising the drug substance, particularly for skin sensitive and...